Earl is learning the hard way that when you do something bad, it has a way of coming back at you ten-fold. Hoping to turn his life around, he gets a list of deeds to make up for it.

Corporate billionaire Edward Cole and working class mechanic Carter Chambers have nothing in common, except they both have been diagnosed with terminal illnesses. While sharing a hospital room together, they decide to make a Bucket List of all the things they have ever wanted to do before they die. In the process of completing the list, both of them heal each other, become unlikely friends, and ultimately find the joy in life.