After kidnapping a father and his two kids, the Gecko brothers head south to a seedy Mexican bar to hide out in safety. But when they face the bar's truly notorious clientele, they are forced to team up with their hostages in order to make it out alive.

In this sequel to Scream, Sidney Prescott thought she'd put the murders that shattered her life behind her, until a copy cat killer begins acting out a real-life sequel.